Author Correction: Broad-spectrum anti-CRISPR proteins facilitate horizontal gene transfer

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Horizontal Gene Transfer

Horizontal gene transfer (HGT) is the movement of genetic information between organisms, a process that includes the spread of antibiotic resistance genes among bacteria (except for those from parent to offspring), fueling pathogen evolution. Many resistance genes evolved long ago in natural environments with no anthropogenic influence but these genes are now rapidly spreading to and among huma...

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Inferring Horizontal Gene Transfer

Horizontal or Lateral Gene Transfer (HGT or LGT) is the transmission of portions of genomic DNA between organisms through a process decoupled from vertical inheritance. In the presence of HGT events, different fragments of the genome are the result of different evolutionary histories. This can therefore complicate the investigations of evolutionary relatedness of lineages and species. Also, as ...

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CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA.

Horizontal gene transfer (HGT) in bacteria and archaea occurs through phage transduction, transformation, or conjugation, and the latter is particularly important for the spread of antibiotic resistance. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci confer sequence-directed immunity against phages. A clinical isolate of Staphylococcus epidermidis harbors a CRISPR spac...

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CRISPR-Cas-Mediated Phage Resistance Enhances Horizontal Gene Transfer by Transduction

A powerful contributor to prokaryotic evolution is horizontal gene transfer (HGT) through transformation, conjugation, and transduction, which can be advantageous, neutral, or detrimental to fitness. Bacteria and archaea control HGT and phage infection through CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR-associated proteins) adaptive immunity. Although the benefi...

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ژورنال

عنوان ژورنال: Nature Microbiology

سال: 2020

ISSN: 2058-5276

DOI: 10.1038/s41564-020-0726-9